"The twelve string guitar produces a richer, more ringing tone than a standard six string guitar. Essentially, it is a type of guitar with a natural chorus effect due to the subtle differences in string timbre between the 12 strings.

The strings are placed in courses of two strings each that are usually played together. The two strings in each bass course are normally tuned an octave apart, while each pair of strings in the treble courses is tuned in unison. The tuning of the second string in the third course (G) varies: some players use a unison string which is less prone to breakage, others prefer the distinctive high-pitched, bell-like quality an octave string makes in this position.

The greater number of strings complicates playing, particularly for the plucking (or picking) hand. The gap between the dual-string courses is usually narrower than that between the single-string courses of a conventional six-string guitar, so more precision is required with pick or fingertip when not simply strumming chords. The pairing of thin, easily broken octave strings with larger, stiffer bass strings presents difficulties to the player also, and only a very skilled player can reliably pluck single strings from within a course at any speed (notably the very high octave G string, which is the highest-pitched string on the instrument). Nevertheless, with practice, the twelve-string guitar is not unduly difficult to play. It is, however, generally used in a fairly restricted role which emphasises its strengths: rich ringing, full-bodied chords, and fast, rippling single plucked notes on the twinned strings" - Darren Curtis Skanson